Chronic migraine prevention with topiramate
نویسندگان
چکیده
منابع مشابه
Topiramate for migraine prevention: an update.
Although the drug topiramate initially was developed for the treatment of epilepsy and received its first US Food and Drug Administration (FDA) approval for that purpose, it subsequently was shown to be effective for the prevention of migraine headaches and is FDA approved for that indication as well. Migraine and epilepsy share a considerable number of biologic and clinical features, and it fo...
متن کاملTopiramate in migraine prevention: results of a large controlled trial.
BACKGROUND Open-label trials and small controlled studies report topiramate's efficacy in migraine prevention. OBJECTIVE To assess the efficacy and safety of topiramate as a migraine-preventive therapy. DESIGN A 26-week, randomized, double-blind, placebo-controlled study. SETTING Outpatient treatment at 49 US clinical centers. Patients Patients were aged 12 to 65 years, had a 6-month Inte...
متن کاملTopiramate for migraine prevention: a randomized controlled trial.
CONTEXT Small open-label and controlled trials suggest that the antiepileptic drug topiramate is effective for migraine prevention. OBJECTIVE To assess the efficacy and safety of topiramate for migraine prevention in a large controlled trial. DESIGN, SETTING, AND PATIENTS A 26-week, randomized, double-blind, placebo-controlled study was conducted during outpatient treatment at 52 North Amer...
متن کاملTopiramate for migraine prophylaxis.
Topiramate is a neurmodulatory compound with neuron stabilizing properties and is approved for the preventive treatment of migraine in several countries [5]. Several small and large trials have reported good efficacy and safety of topiramate in migraine prophylaxis in adults [6]. The present study was done to study the role of topiramate in migraine prophylaxis in children who either failed to ...
متن کاملChronic migraine headache prevention with noninvasive vagus nerve stimulation
OBJECTIVE To evaluate the feasibility, safety, and tolerability of noninvasive vagus nerve stimulation (nVNS) for the prevention of chronic migraine (CM) attacks. METHODS In this first prospective, multicenter, double-blind, sham-controlled pilot study of nVNS in CM prophylaxis, adults with CM (≥15 headache d/mo) entered the baseline phase (1 month) and were subsequently randomized to nVNS or...
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ژورنال
عنوان ژورنال: The Journal of Headache and Pain
سال: 2006
ISSN: 1129-2369,1129-2377
DOI: 10.1007/s10194-006-0339-6